Wine, especially the red variety, has been studied extensively over many years with impressive findings suggesting it may promote a longer lifespan, protect against certain cancers, improve mental health, and provide benefits to the heart.
A brief history of wine
According to Cornell University, archeologists date grape cultivation and wine making to sometime between 6,000 and 4,000 BC in Mesopotamia and the coastal areas of the Caspian Sea. At that time only aristocrats, royalty, and members of clergy enjoyed wine while peasants and commoners drank ale, mead and beer.
Jancis Robertson, in "The Oxford Companion to Wine, 3rd Edition"2, wrote that ancient Egyptian Papyri and Sumerian tablets dating back to 2200 BC are the oldest documents that mention wine as a man-made medicine. In ancient Egypt, wine was also savored mainly by royalty and the upper classes.
When wine making arrived in ancient Greece, it was enjoyed by the whole spectrum of society, and became a popular theme in literature, religion, leisure, medicine and mythology.
Hippocrates, often referred to as the "father of western medicine", promoted wine as part of a healthy diet. He also claimed that wine was good for disinfecting wounds, as well as a liquid in which medications could be mixed and taken more easily by patients. Hippocrates said wine should be used to alleviate pain during childbirth, for symptoms of diarrhea, and even lethargy.
The ancient Romans took vine clippings from Greece back to Rome. From there centers of viticulture soon appeared all over southern Europe, then in Germany and the rest of the continent.
In the Bible, in his first epistle to Timothy, Paul the Apostle recommended a little wine every now and then to help digestion.
Persian Avicenna in the 11th century AD acknowledged that wine helped digestion, but only recommended it as a disinfectant while dressing wounds because Islamic laws prohibited the consumption of alcohol.
During the Middle Ages, Catholic monks frequently used wine for a wide range of medical treatments.
Wine was so linked to medical practice that in the first printed book on wine, Arnaldus de Villa Nova (circa. 1235-1311 AD), a physician, wrote at length on wine's benefits for the treatment of many illnesses and conditions, including sinus problems and dementia.
One of the reasons wine was so popular throughout history is because safe drinking water was often scarce. During the 1892 cholera epidemic in Hamburg, Germany, wine was used to sterilize water.
The 1800s and early twentieth century saw a rapid spread of the Temperance movement, admonishing the use of alcoholic beverages and advising reduced consumption. Medical establishments began recognizing alcoholism as a disease.
The harms of alcohol have also been well documented throughout history. In Islam, the Qur'an (Koran) forbade the consumption of alcohol through several separate verses revealed at different times. Benjamin Rush3 (1745-1813), a signatory of the United States Declaration of Independence, said "My observations authorize me to say, that persons who have been addicted to them (spirits), should abstain from them suddenly and entirely. 'Taste not, handle not, touch not' should be inscribed upon every vessel that contains spirits in the house of a man, who wishes to be cured of habits of intemperance".
What is moderate wine consumption?
"Moderate" wine consumption is said to be good for the health. However, what is "moderate" wine consumption? How much wine you can drink in one sitting before the health benefits turn into dangers depends on many factors, including the person's size, age, sex, body stature and general state of health, as well as whether it is being consumed with food or on an empty stomach.
Women absorb alcohol more rapidly than men, because of their lower body water content and different levels of stomach enzymes. Therefore, moderate wine consumption will be a lower amount for women than for men.
According to "Dietary Guidelines for Americans 2010", published by the US Department of Agriculture, "If alcohol is consumed, it should be consumed in moderation - up to one drink per day for women and two drinks per day for men".
The National Health Service5, UK, writes "Men should not regularly drink more than 3-4 units of alcohol a day. Women should not regularly drink more than 2-3 units a day." One unit equals 10ml or 8g of pure alcohol. A 250ml (large) glass of 12% red wine has about 3 units of alcohol. A 175ml (medium) glass has about two units.
All the health benefits associated with drinking wine listed below are only applicable to moderate drinking!
What are the benefits of drinking wine?
1. Reducing risk of depression
A team from several universities in Spain reported in the journal BMC Medicine that drinking wine may reduce the risk of depression. The researchers gathered data on 2,683 men and 2,822 women aged from 55 to 80 years over a seven-year period. The participants had to complete a food frequency questionnaire every year, which included details on their alcohol consumption as well as their mental health. The authors found that men and women who drank two to seven glasses of wine per week were less likely to be diagnosed with depression. Even after taking into account lifestyle factors, which could influence their findings, the significantly lower risk of developing depression still stood.
2. Preventing colon cancer
Scientists from the University of Leicester, UK, reported at the 2nd International Scientific Conference on Resveratrol and Health that regular, moderate red wine consumption can reduce the rate of bowel tumors by approximately 50%.
Researchers from Harvard Medical School reported that red wine has anti-aging properties. Specifically, resveratrol was the compound found to have the beneficial effect. The resveratrol in wine comes from the skins of red grapes. Blueberries, cranberries and nuts are also sources of resveratrol. Head investigator, David Sinclair said, "Resveratrol improves the health of mice on a high-fat diet and increases life span." Their findings, which were published in the journal Cell Metabolismoffer, was the first compelling proof of the definite link between the anti-aging properties of resveratrol and the SIRT1 gene.
Wine's anti-aging properties have been talked about for over one thousand years. Monasteries throughout Europe were convinced that their monks' longer lifespans, compared to the rest of the population, was partly due to their moderate, regular consumption of wine. A study carried out at the University of London found that procyanidins, compounds commonly found in red wine, keep the blood vessels healthy and are one of the factors that contribute towards longer life spans enjoyed by the people in Sardinia and the southwest of France. The researchers also found that red wine made in the traditional way has much higher levels of procyanidins than other wines.
4. Protecting your heart
Red wine contains resveratrol, a powerful antioxidant compound. Resveratrol also protects your heart and arteries against the effects of saturated fat in your diet, so drinking one or two glasses of red wine a day can help protect your heart and prevent cardiovascular disease.
The flavonoids and sapponins in red wine also help to protect your heart against cardiovascular disease. The alcohol in red wine, when consumed in moderation, raises your levels of "good" HDL cholesterol, helps prevent the formation of blood clots and can help to protect your arteries from the damage caused by "bad" LDL cholesterol.
5. Preventing dementia
A team from Loyola University Medical Center found that moderate red wine intake could reduce the risk of developing dementia. In this study, the researchers gathered and analyzed data from academic papers on red wine since 1977. The studies, which spanned 19 nations, showed a statistically significantly lower risk of dementia among regular, moderate red wine drinkers in 14 countries.
The investigators explained that resveratrol reduces the stickiness of blood platelets, which helps keep the blood vessels open and flexible. This helps maintain a good blood supply to the brain. Both white and red wines contain resveratrol, but red wine has much more. The skin of red grapes has very high levels of resveratrol. During the manufacturing process of red wine, there is prolonged contact with grape skins.
Lead investigator, Professor Edward J. Neafsey, said, "We don't recommend that nondrinkers start drinking. But moderate drinking, if it is truly moderate, can be beneficial." Neafsey and colleagues wrote in The Journal of Neuropsychiatric Disease and Treatment that moderate red wine drinkers had a 23% lower risk of developing dementia compared to people, who rarely or never consumed the alcoholic beverage.
6. Protecting from severe sunburn
Wine and grape derivatives can help reduce the damaging effects of UV (ultraviolet) light, scientists from the University of Barcelona in Spain reported in The Journal of Agricultural Food and Chemistry. The authors explained that when UV rays make contact with human skin, they activate reactive oxygen species (ROS), which oxidize fats, DNA and other large molecules, which in turn stimulate other enzymes that harm skin cells. Flavonoids, found in wine and grapes, inhibit the formation of the ROS in skin cells that are exposed to sunlight.
7. Preventing blinding diseases
Red wine can stop the out-of-control blood vessel growth in the eye that causes blindness, researchers at Washington University School of Medicine in St. Louis reported in the American Journal of Pathology. Diabetic retinopathy and age-related macular degeneration, which is the leading cause of blindness among Americans aged 50+ years, are caused by an overgrowth of blood vessels (angiogenesis) in the eye. The researchers explained that resveratrol is the compound in wine that protects vision. Grapes, blueberries, peanuts and some other plants are rich in resveratrol.
8. Damage after stroke
Red wine may protect the brain from stroke damage, researchers at Johns Hopkins University School of Medicine wrote in the journal Experimental Neurology. Professor Sylvain Doré believes that resveratrol in red wine raises levels of heme oxygenase, an enzyme known to protect nerve cells in the brain from damage. When somebody suffers a stroke, the brain is ready to protect itself because of higher enzyme levels. Doré added that nobody yet knows, whether it is just the resveratrol that has the health benefits, or it is the alcohol in the wine, which may be needed to concentrate the levels of the compound.
9. Improving lung function and preventing lung cancer
Dutch scientists reported on a study that looked at the effects of resveratrol, red wine, and white wine on lung function. They found that: 1) Pure resveratrol was good for lung function; 2) White wine was also good for lung function; 3) Red wine made no difference.
A reviewer of the study wrote, "Resveratrol may well be just the bystander of something else present in wine. The beneficial effects on lung function are probably related to many compounds present in wine, and not just resveratrol." According to a number of scientific studies, moderate wine drinkers appear to enjoy better lung function, the authors added.
In another study, a team from Kaiser Permanente wrote in the journal Cancer Epidemiology, Biomarkers and Prevention that red wine consumption may reduce lung cancer risk. Chun Chao, Ph.D., said, "An antioxidant component in red wine may be protective of lung cancer, particularly among smokers."
10. Raising levels of omega-3 fatty acids
Wine is better than other alcoholic drinks in raising levels of omega-3 fatty acids in plasma and red blood cells, according to the IMMIDIET study involving European researchers from various countries. The study, published in the American Journal of Clinical Nutrition, examined 1,604 adults from London in England, Abruzzo in Italy, and Limburg in Belgium. They all underwent a comprehensive medical examination with a primary care physician (general practitioner) and also completed an annual food frequency questionnaire, which included details of their dietary and drinking habits. They found that regular, moderate wine drinkers had higher blood levels of omega-3 fatty acids, which are usually derived from eating fish. We know that omega-3 fatty acids protect against coronary heart disease.
The scientists found that drinking wine acts like a trigger, boosting levels of omega-3 fatty acids in the body.
11. Preventing liver disease
A study carried out at the UC San Diego School of Medicine concluded that modest wine consumption reduced the risk of non-alcoholic fatty liver disease by half compared to people who never drank wine. Their finding challenged conventional thinking regarding alcohol consumption and liver health. The researchers reported in the journal Hepatology that regular, modest beer or liquor drinkers had more than four times the risk of non-alcoholic fatty liver disease compared to the wine drinkers.
12. Protecting from prostate Cancer
A study published in the June 2007 issue of Harvard Men's Health Watch reported that male moderate red wine drinkers were 52% as likely to be diagnosed with prostate cancer as men who never drank red wine. They defined moderate drinking as an average of four to seven glasses of red wine per week. Initially, the Seattle researchers looked at general alcohol consumption and found no link to prostate cancer risk. However, when they went one-step further and looked at different alcoholic beverages, they identified a clear association between red wine drinking and lower prostate cancer risk. Even extremely moderate red wine consumption (one glass per week) reduced men's risk of prostate cancer by 6%, the authors informed.
13. Preventing type 2 diabetes
In an animal experiment, scientists at the Chinese Academy of Sciences discovered that a chemical found in red wine and the skin of red grapes - resveratrol - improved sensitivity to insulin. Insulin resistance is the most important critical factor contributing to type 2 diabetes risk. The researchers reported in the journal Cell Metabolism that resveratrol also increased levels of the enzyme SIRT1, which was found to improve insulin sensitivity in mice. Study leader, Qiwei Zhai said that red wine might have some benefits for insulin sensitivity, but this needs to be confirmed in further studies.
14. Protecting against neurological disorders
Researchers have found that resveratrol can help block the formation of amyloid plaques, which are thought to damage brain cells and contribute to Alzheimer's disease. Another study found that resveratrol actually aided in the formation of new nerve cells, which could help prevent neurological disorders like Alzheimer's and Parkinson's disease.
15. Teeth health
Red wine, even nonalcoholic red wine, hardens your enamel to prevent tooth decay. Hardened enamel is more resistant to Streptococcus mutans, the bacteria, which lives on your teeth and is responsible for tooth decay. The polyphenols in red wine can also prevent gum disease, and even help to treat it by reducing inflammation in the gums.
16. Protecting from acne
A study published in the journal Dermatology and Therapy claims a compound derived from red grapes and found in red wine - resveratrol - may be an effective treatment for acne, particularly when combined with an already existing medication for the disorder.
17. Advanced skin care and more benefits through vinotherapy
According to one of the researchers, polyphenol forms a protective layer on skin and stimulates the renewals of cells and collagen. Pholyphenol also clears up free radicals, which damage and age cells. One of the newly popular wine therapies is so called vinotherapy, when you do not consume the product, but apply it externally as a wine bath. According to practitioners of vinotherapy, wine when applied externally, can help shift cellulite, tone our body and reduce wrinkles and fine lines. This is because, they say, polyphenols extracted from grape seeds are a powerful antioxidant - our body's defenses against highly reactive molecules that can lead to premature ageing.
Vinotheray is also being used in spas in conjunction with ayurvedic therapies to soothe frayed nerves and relax the stressed tissues as a passive form of exercise. The procedure helps in the production of anti-bodies, soothes the nervous system, improves circulation and builds up the immune system.
The Key Word – Moderation
While you learnt how good wine is for your health, remember that this footnote disclaimer is very important. By abusing the habit consuming more than moderate or recommended amounts, may lead to serious negative consequences to your health. Note that
Drinking alcohol can lead to alcohol abuse in some people. Excessive alcohol consumption is also associated with an increased risk of cancer, high triglycerides, obesity, liver disease, car accidents, high blood pressure, heart failure, stroke, physical abuse, irregular heart rhythms, suicide and swelling of the pancreas.
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